The FLT3-Q Real-Time PCR Kit is a CE-IVD molecular diagnostic assay designed for the detection of FLT3 gene alterations, including Internal Tandem Duplications (ITD) and Tyrosine Kinase Domain (TKD) mutations.
This assay supports risk stratification and treatment planning in Acute Myeloid Leukemia (AML) by enabling rapid identification of clinically actionable FLT3 mutations through a real-time PCR workflow.
The FLT3-Q Real-Time PCR Kit is an in vitro diagnostic (IVD) assay based on real-time PCR technology for qualitative detection of key FLT3 mutations in genomic DNA extracted from peripheral blood samples.
FLT3 mutations lead to constitutive activation of the FLT3 receptor, promoting leukemic cell proliferation and survival.
The assay combines Real-time PCR detection, Mutation-specific probe chemistry and Size-based mutation analysis (for ITD) to deliver comprehensive FLT3 mutation screening.
FLT3 is one of the most clinically significant mutations in Acute Myeloid Leukemia (AML).
It is present in ~20–30% of AML cases and is ssociated with:
FLT3 mutation testing supports:
TThe kit is ideal for clinical molecular laboratories performing:
Simultaneous screening for both FLT3-ITD and FLT3-TKD alterations.
Enables clinicians to classify patients into prognostic and therapeutic risk categories.
Tube 1: TKD mutation detection via real-time PCR
Tube 2: ITD detection via size-based PCR product analysis
ITD mutations create variable amplicon lengths, enabling visual differentiation from wild type bands.
Validated for use with Peripheral blood (EDTA)
The assay provides clear qualitative mutation reporting, including:
Designed for automated workflow including extraction and amplification.
| Commercial Name | Old Cat No. | New Cat No. | Pack Size |
|---|---|---|---|
| FLT3-Q Real-Time PCR Kit | G2M709021R | G610025-3 | 24 Tests |
If your lab requires a reliable FLT3 mutation PCR kit for AML molecular testing, this assay delivers:
Download useful documents and technical information for the FLT3-Q Real-Time PCR Kit.
Since its inception in 2016, Genes2me has been constantly striving towards setting a benchmark in the diagnostics space by introducing premium quality (Made in India) diagnostic kits which are CE-IVD, ISO-13485:2016, and ISO 9001:2015 certified, assuring our clients of unparalleled quality and compliance with international standards.
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