EZY AutoPrep - 48

Automated NGS Library Sample Preparation
EZY AutoPrep - 48

Overview


EZY AutoPrep-48 is a high-throughput automated NGS Library Preparation Workstation capable of performing 48 library preps in one run, designed for laboratories that demand greater capacity without compromising precision, reliability, or ease of use. Built as an advanced extension of the EZY AutoPrep platform, it enables scalable library preparation with significantly reduced hands-on time for medium- to high-throughput sequencing workflows.

In addition to all the integrated capabilities of EZY AutoPrep-24, EZY AutoPrep-48 features a larger, more flexible deck layout, a high-performance 24-channel pipetting head, and an on-board fluorometer module for integrated quantification. The system seamlessly combines built-in thermal cycling, temperature-controlled deck positions, incubation and shaking, and gripper-based material handling to automate the complete NGS library preparation workflow—from end repair and adapter ligation to PCR amplification, cleanup, and quantification.

By unifying high-density liquid handling, advanced thermal control, integrated quantification, and an intuitive software interface, EZY AutoPrep-48 streamlines complex NGS workflows while maximizing consistency and reproducibility. The result is a powerful, walk-away automation solution that delivers higher throughput, improved data quality, and faster turnaround times for modern sequencing laboratories scaling their operations.

Features


  • Fully Integrated Workflow: Automates the complete NGS library preparation process—from end repair and adapter ligation to PCR amplification, cleanup, and on-deck quantification—eliminating manual transfers and workflow interruptions.
  • On-Board Quantification: The built-in fluorometer module allows real-time, on-deck library quantification, improving process control and reducing dependency on external instruments.
  • Advanced Contamination Control: Integrated HEPA filtration and UV decontamination create a clean working environment, minimizing the risk of cross-contamination and ensuring reliable, high-quality results.
  • Intelligent Software & Walk-Away Operation: An Open, intuitive, user-friendly interface with flexible protocol configuration enables true walk-away automation, simplifying complex workflows and improving operational efficiency, at the same time allowing users to create their own protocols.

High Precision 24-Channel Pipette for Fast, Accurate Pipetting

PC Operation

Integrated On-Deck Fluorimeter Module for Seamless Library Quantification

Automated Efficiency

Applications


NGS Library Preparation

Automates end-to-end NGS library preparation workflows with high precision, reproducibility, and minimal hands-on time.

DNA & RNA Extraction

Supports automated magnetic bead–based extraction and purification of DNA, RNA, and cell-free nucleic acids.

PCR & qPCR Setup

Enables accurate and contamination-controlled preparation of PCR and qPCR reactions for consistent amplification results.

ELISA & Plate-Based Assays

Automates reagent dispensing, incubation, and washing steps for ELISA and other plate-based immunoassays.

NGS LIBRARY CONSTRUCTION WORKFLOW

01 EP-ER/A
02 Adaptor
Ligation
03 Purification
04 PCR
Amplification
05 Purification
06 Library
Pooling
07 Hybridization
08 Post
Clean-Up
09 PCR
Amplification
10 Purification
11 Quantify
Hybridized
Library
EZY AutoPrep - 48 is capable of performing the whole process of library construction except for "Library Pooling"
EZY AutoPrep - 24 is capable of performing all steps except "Library Pooling & Quantitation"

Specifications


Model No. EZY AutoPrep-48
Throughput: 48
Deck Locations: 24
Compatible Consumble: SBS standard 96 well plate, deep well plate, reservoirs etc.
Tips: 200µL and 50µL
Magnetic plate: 96-well annular magnetic plate
XYZ Robot: X-axis Repeated Positioning Precision: ±0.1 mm
Y-axis Repeated Positioning Precision: ±0.1 mm
Z-axis Repeated Positioning Precision: ±0.1 mm
Pipettor: 24-channel fixed spacing pipettors
Air displacement pipetting technology
Pipetting range 2 - 200 µL
Precision(CV) 2 µL: ≤5% , 100 µL: ≤1%, 200 µL: ≤1%
Gripper: Motorized Gripper for automated consumable transfer and handling
Temperature control module: Including 2 temperature control blocks.
Temperature control range: 4~75°C
Temperature control accuracy: ±1°C
Temperature control uniformity: ±1°C
Fluorescence detection module: Simultaneous detection of 8 samples, 2-20µL sample, 0.4 ng~100 ng
Heating & Oscillation Module: (Room Temperature +5°C ) ~ 99°C
Temperature Accuracy: ±2.0°C ;
Temperature Uniformity: ≤ 1.5°C ;
Oscillation Speed: 200rpm to 2000rpm
PCR Module: Temperature Range: Lid: 30°C~ 105°C,
Module: 4°C~ 99°C
Uniformity: ≤ 1°C
Accuracy: ± 0.5°C
Applications: NGS Library Prepration, Nucleic Acid Extraction, PCR Setup, Elisa Setup and more
UV sterilization: Equipped with UV sterilization lamp, high-efficiency purification filter device
Interface: Integrated 14” Colour Touch Screen Windows PC
Instrument port: USB port, CAN communication
Ambient condition: Temperature requirement: 20±5°C, humidity: ≤80 %
Instrument Weight: 200Kg
Dimension (W×D×H): 1180mm W x 860mm D x 955mm H
Power input: 100~240 V, 50~60 Hz, rated power 2000 W

Ordering Information


Cat No.

Commercial Name

G2MBR4-0712

EZY AutoPrep - 48 Automated NGS Library Preparation Workstation

G2MBR4-0660

EZY AutoPrep - 24 Automated NGS Library Preparation Workstation

Resources


Product Enquiry Form


Other Products


Since its inception in 2016, Genes2me has been constantly striving towards setting a benchmark in the diagnostics space by introducing premium quality (Made in India) diagnostic kits which are CE-IVD, ISO-13485:2016, and ISO 9001:2015 certified, assuring our clients of unparalleled quality and compliance with international standards.


© 2025 Genes2me. All rights reserved.