RapiCycler 96
RapiCycler 96 is engineered to meet the demanding requirements of advanced molecular laboratories. Available with 4 or 6 fluorescence channel configurations, capable of providing flexibility needed for diverse assay designs and multiplex workflows.
Designed for efficiency and precision, the system processes up to 96 samples per run, making it ideal for high-throughput testing environments. It supports a comprehensive range of applications, including qualitative and quantitative analysis, absolute and relative quantification, melting curve analysis, standard curve and dissociation curve analysis, multiplex PCR, SNP genotyping, high-resolution melting, allele discrimination, and temperature gradient optimization.
Powered by advanced semiconductor-based thermal control technology, RapiCycler 96 ensures rapid ramp rates and exceptional temperature uniformity for consistent amplification performance. Its high-sensitivity photoelectric detection system enables accurate real-time fluorescence monitoring across all channels. Combined with robust, intuitive, easy to use analysis software, the system delivers precise, reproducible, and reliable results for both research and diagnostic applications.
Developed with a deep understanding of both clinical and research needs, G2M’s Whole exome sequencing assay is designed with exceptional uniformity and high on-target efficiency with the panel content aligned with the latest curated genomic data for enhanced clinical relevance. The panel encompasses ~21,500 genes catering to various hereditary conditions and germline cancers.
An open RT-PCR system enables highly sensitive and specific detection of viral, bacterial, and genetic targets. It supports validated diagnostic assays as well as laboratory-developed tests (LDTs), making it ideal for hospitals, reference labs, and public health facilities requiring flexible test menus.
From respiratory pathogens to emerging outbreaks, the system delivers rapid and reliable pathogen identification. Its open platform allows laboratories to adapt quickly to new targets, ensuring preparedness for evolving public health challenges.
The instrument supports precise detection of gene mutations, expression profiling, and minimal residual disease monitoring. Its high sensitivity enables early detection of cancer-associated biomarkers, supporting personalized medicine and targeted therapy decisions.
Designed for versatility, the platform detects microbial contamination and genetically modified organisms (GMOs) in food, water, and environmental samples. It ensures compliance with regulatory standards while maintaining throughput and reproducibility.
Ideal for gene expression studies, RNA quantification, and pathway analysis, the system provides researchers with flexibility in assay design. Its open chemistry format allows compatibility with a wide range of reagents and protocols.
The instrument enables accurate detection of animal pathogens and supports herd health monitoring programs. Its adaptability makes it suitable for veterinary diagnostics, zoonotic disease surveillance, and livestock management.
| Model No. | G2MRAPI4001 | G2MRAPI4002 |
| Sample Capacity | 96 well, 12 × 8 strip, 96 × 0.2 ml single tube | |
| Consumables | 0.2 ml tube, 0.2 ml 8-tube strips, 0.2 ml 96-well plate | |
| Reaction Volume | 5–100 µl | |
| Temperature Range | 4–105 °C (Resolution: 0.1 °C) | |
| Ramp Rate | Up to 8.0 °C/s | |
| Temperature Control Accuracy | ±0.1 °C | |
| Uniformity | ±0.2 °C | |
| Accuracy | ±0.1 °C | |
| Gradient | 0.1–42 °C | |
| Hot Lid Temperature | 30–110 °C (Adjustable, default 105 °C) | |
| Hot Lid Opening Mode | Automatic cover opening | |
| Temperature Control | Block / Tube | |
| Excitation Wavelength | 400–710 nm | |
| Emission Wavelength | 500–810 nm | |
| Detection Channels | 4 Channels | 6 Channels |
| Factory Calibrated Dyes |
F1: FAM / SYBR Green / EVA Green F2: HEX / VIC / JOE / TET / YELLOW / NED F3: ROX / Texas Red F4: Cy5 / Quasar 670 |
F1: FAM / SYBR Green / EVA Green F2: HEX / VIC / JOE / TET / YELLOW / NIC F3: ROX / Texas Red F4: Cy5 / Quasar 670 F5: Cy5.5 / Quasar 705 F6: CY3 / NED / TAMRA |
| Excitation Source | Long-life LED | |
| Detection Method | High-sensitivity photoelectric detector | |
| Dynamic Range | 1–1010 copies | |
| Sensitivity | 1 copy | |
| Feature Functions | Qualitative/absolute quantification, relative quantitative, genotyping, HRM, melting curve, multiplex PCR, standard curve, relative standard curve, comparative Ct, allele identification/SNP genotyping, temperature gradient function, dissociation curve analysis, pathogen detection, plus/minus assays etc. | |
| Special Temperature Functions | Supports thermal gradient PCR, Long PCR, Touch Down PCR | |
| Control Mode | 12.1 inch adjustable colour touch screen control or PC control | |
| Data Export Formats | Excel, CSV, TXT, PDF | |
| Reporting | Automated report generation at the end of the run, ready for printing | |
| Communication Ports | USB 2.0, RS232 | |
| PC Operating System | Windows 7, Windows 10 | |
| Dimensions (L × W × H) | 520 × 350 × 330 mm | |
| Net Weight | 30 kg | |
| Power Supply & Consumption | AC 100–240 V, 50–60 Hz; 1500 W | |
| Powerful software | Pre-calibrated with optimized algorithms to calculate crosstalk coefficients, ensuring minimal interference from overlapping fluorescence dyes accurate detection | |
| Data Collection | Synchronous multi-channel detection with side-scan technology captures fluorescence data for 96 samples in 5 seconds. All channels are collected by default, with post-run reconfiguration and reanalysis available | |
Relative gene expression analysis across multiple samples using ΔΔCt method.
Standard curve demonstrating high amplification efficiency and linear quantification.
Melting curve confirming specificity of PCR products through peak analysis.
Allelic discrimination plot for SNP genotyping and sample classification.
| Document | Action |
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RapiCycler 96 — Specifications Channel configurations, throughput, and ordering SKUs |
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Operation & Software Manual Setup, run programming, and analysis software walkthrough |
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Fluorescence Channel Performance Crosstalk correction, dye compatibility, detection sensitivity |
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Multiplex PCR & SNP Genotyping Assay design for multiplexed and allele-discrimination workflows |
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High-Throughput Diagnostic Deployment Reference laboratory results running RapiCycler 96 at scale |
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Since its inception in 2016, Genes2me has been constantly striving towards setting a benchmark in the diagnostics space by introducing premium quality (Made in India) diagnostic kits which are CE-IVD, ISO-13485:2016, and ISO 9001:2015 certified, assuring our clients of unparalleled quality and compliance with international standards.
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