Streptococcus pneumoniae infection remains a major cause of respiratory tract infections worldwide, particularly among elderly individuals, young children, and immunocompromised patients. While Streptococcus pneumoniae may asymptomatically colonize the upper respiratory tract in healthy carriers, invasive infection can lead to serious clinical conditions including pneumonia, meningitis, bacteremia, and sepsis. Early and accurate molecular detection is therefore essential for timely diagnosis, antimicrobial management, and improved patient outcomes.
The S. Pneumonia-Q Real-Time PCR Kit from Genes2Me is an in vitro diagnostic assay designed for the qualitative detection of Streptococcus pneumoniae-specific DNA in clinical samples using real-time PCR technology. The assay enables rapid, sensitive, and specific detection of pneumococcal DNA in a single-tube reaction, supporting reliable diagnosis of pneumococcal infections in routine clinical laboratory settings.
The S. Pneumonia-Q Real-Time PCR Kit utilizes real-time PCR technology for the specific detection of Streptococcus pneumoniae DNA in clinical specimens in a single-tube reaction format. It consists of specific primers for the detection of S. Pneumonia specific target sequences in a single tube. The fluorescent probes are labelled with distinguishable dye for the detection of S. Pneumonia (SP) specific DNA as well as for the detection of Internal Control.
Real-time fluorescence monitoring enables rapid amplification and detection of target nucleic acid during PCR cycling.
Traditional culture-based methods for detecting Streptococcus pneumoniae may require extended turnaround times and can be affected by low bacterial load in clinical specimens. Real-time PCR enables rapid and highly sensitive detection of pneumococcal DNA, supporting earlier diagnosis and clinical intervention. The assay’s highly specific primer and probe design minimizes non-specific amplification. Integrated internal control monitoring further strengthens assay reliability by identifying PCR inhibition. Rapid molecular identification of pneumococcal infections supports timely antimicrobial management, infection control measures, and improved patient care, particularly in high-risk populations vulnerable to severe pneumococcal disease.
Designed with specific primers and fluorescent probes for sensitive and accurate detection of pneumococcal DNA in clinical samples.
Integrated HEX-labelled internal control monitors PCR inhibition, reducing the risk of false-negative results.
Target detection and internal control amplification are performed simultaneously within one reaction tube, improving workflow simplicity and minimizing contamination risk.
Validated on multiple real-time PCR systems including QuantStudio 5 Real-Time PCR System, CFX96 Real-Time PCR System, LightCycler 480 System and RapiCycler 96 Real Time PCR System.
Supplied with primer-probe mixes, internal control reagents, positive control template, qRT-PCR master mix, and RNase/DNase-free water for standardized assay setup and reliable performance.
Ct value of ≤35 supports dependable qualitative detection of pneumococcal DNA, including low bacterial load specimens.
S. Pneumonia-Q Real-Time PCR specific amplification plot of Treponema pallidum Positive Control (HEX Channel) along with Internal Control (Cy5 Channel)
| Commercial Name | Old Cat No. | New Cat No. | Pack Size |
|---|---|---|---|
| S. Pneumonia-Q Real-Time PCR Kit | G2M706921 | G2M706921 | 50 Tests |
Since its inception in 2016, Genes2me has been constantly striving towards setting a benchmark in the diagnostics space by introducing premium quality (Made in India) diagnostic kits which are CE-IVD, ISO-13485:2016, and ISO 9001:2015 certified, assuring our clients of unparalleled quality and compliance with international standards.
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