MagNXT Cell-free DNA Extraction

MagNXT Cell-free DNA Extraction

MagNXT Cell-Free DNA Extraction Kit is designed for efficient isolation and purification of circulating cell-free DNA (cfDNA) from human plasma and serum samples. The kit uses advanced superparamagnetic bead-based technology to ensure high yield, purity, and reproducibility, making it suitable for both clinical diagnostics and research applications.

Kit components: MagPure Particles | Buffer CLB-3 | Buffer CW1 | Buffer CW2 | Buffer EB | Proteinase K | Carrier RNA | Proteinase Dissolving Buffer

Blood DNA Extraction

Overview

MagNXT Cell-free DNA Extraction Kit is designed for efficient isolation and purification of circulating cell-free DNA (cfDNA) from human plasma and serum samples. The kit is based on superparamagnetic bead based technology, ensuring high recovery, reproducibility, and compatibility with both manual workflows and open liquid-handling platforms. Purified cfDNA is free from inhibitors and suitable for a wide range of downstream molecular applications, making it ideal for clinical diagnostics as well as research use.

Product Features

Blood DNA Extraction Kits
  • Recommended Input Amount: ~500μl Plasma/Serum (Depends upon the type of sample used)
  • Binding Mechanism: Super paramagnetic beads
  • Elution Volume: 30 - 50 µl
  • Purity: A260/280 -1.8±0.1, A260/280 -2.0±0.1
  • Expected Yield: ≥0.6μg Depending upon the type, quality & quantity of the starting material used

Applications

PCR (Polymerase Chain Reaction)

  • Extracted cfDNA can be used for amplification-based assays
  • Provides reliable template DNA for molecular detection workflows

qPCR (Quantitative PCR)

  • High-purity cfDNA supports accurate and reproducible quantitative analysis
  • Compatible with real-time PCR-based diagnostic assays

Next-Generation Sequencing (NGS)

  • Suitable for library preparation from cfDNA
  • Enables downstream sequencing-based analysis for clinical and research use

Southern Blotting

  • Purified cfDNA is compatible with blotting-based DNA analysis techniques
  • Supports hybridization-based detection methods

Microarray Analysis

  • High-quality cfDNA suitable for microarray hybridization
  • Enables genome-wide analysis applications

Clinical & Research Use

Applicable for clinical and research purposes including:

  • Cancer diagnostics and monitoring
  • Autoimmune disease evaluation
  • Prenatal diagnostics

Panel Specifications

Format: Paramagnetic Beads
Technology: Magnetic Bead Base
Sample Type: Plasma & Serum.
Yield: >0.6 µg (depending upon the type, quality & quantity of the starting material used)
Target: Circulating Cell Free DNA
A260/280: 1.6–1.9
Available Pack Sizes: 50 Rxn, 250 Rxn
Throughput Compatibility: Manual

Workflow / How It Works

Extraction workflow

Data Analysis and Reporting

MagNxt Cell free DNA Bioanalyzer
DNA Bioanalyzer

Ordering Information

Commercial Name Cat No. Pack Size
MagNXT Cell Free DNA extraction kit G2M810003-50T 50 Preps
MagNXT Cell Free DNA extraction kit G2M810003-250T 250 Preps

Product Enquiry Form

Resources to get started

Product Brochure
IFU (Instructions for Use)
Data File

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Since its inception in 2016, Genes2me has been constantly striving towards setting a benchmark in the diagnostics space by introducing premium quality (Made in India) diagnostic kits which are CE-IVD, ISO-13485:2016, and ISO 9001:2015 certified, assuring our clients of unparalleled quality and compliance with international standards.

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