Mutations in the NRAS gene play a critical role in the development and progression of several cancers, most notably melanoma and colorectal cancer. Found in 15 - 25% of melanomas and 2 - 6% of colorectal tumors, NRAS mutations are associated with resistance to targeted therapies and are recognized as negative prognostic markers in various cancers. Given their impact on treatment outcomes, accurate detection of these mutations is now a crucial part of precision oncology and clinical decision-making.
To address this need, Genes2Me presents the NRAS-Q Real-Time PCR Kit, an advanced in vitro diagnostic solution designed for the sensitive and specific detection of nine clinically significant NRAS mutations across codons 12, 13, 59, 61, 117, and 146 in exons 2, 3, and 4. The kit is validated for use with FFPE and fresh clinical samples, making it an ideal tool for both routine diagnostics and advanced molecular oncology applications.
The NRAS-Q Real-Time PCR kit uses allele-specific PCR with mutation-targeted FAM probes and an integrated HEX-labeled internal control to deliver precise, reliable mutation detection while continuously monitoring DNA quality and PCR performance. A streamlined workflow with seven ready-to-use mixes, including controls, ensures consistent results, high reproducibility, and minimal hands-on time.
The NRAS-Q Real-Time PCR Kit empowers laboratories and oncologists with a robust, clinically validated, and easy-to-use solution for mutation detection. By providing accurate insights into NRAS mutation status, it helps optimize cancer treatment strategies and supports the global shift towards personalized oncology care.
Detects nine clinically relevant NRAS mutations for confident molecular profiling.
A robust, clinically validated, and easy-to-use solution that enables accurate NRAS mutation assessment, supports optimized treatment decisions, and advances personalized oncology care.
Integrated process control continuously monitors assay performance, ensuring accurate and reproducible results.
Enables reliable detection of low-frequency variants, even in challenging samples.
Validated on leading real-time PCR systems, including Thermo Fisher QuantStudio™ 5, Bio-Rad CFX96, Roche LightCycler® 480, and Genes2Me RapiCycler 96.
Pre-mixed, ready-to-use reagents simplify assay setup, reduce hands-on time, and minimize user error.
| Commercial Name | Cat No. | Pack Size |
|---|---|---|
| NRAS-Q Real-Time PCR Kit | G610023 | 25T |
Download useful documents and technical information of NRAS-Q Real-Time PCR Kit.
Since its inception in 2016, Genes2me has been constantly striving towards setting a benchmark in the diagnostics space by introducing premium quality (Made in India) diagnostic kits which are CE-IVD, ISO-13485:2016, and ISO 9001:2015 certified, assuring our clients of unparalleled quality and compliance with international standards.
© 2025 Genes2me. All rights reserved.
