The AML1 Fusion Real-Time PCR Test Kit is an advanced in vitro diagnostic solution developed for the detection of TEL-AML1 fusion genes in clinical samples. Leveraging highly sensitive and precise Real-Time PCR technology, this assay delivers fast, accurate, and reproducible results. It plays a vital role in the early diagnosis and prognosis of Acute Lymphoblastic Leukemia (ALL), making it particularly significant in pediatric oncology where timely intervention can greatly improve patient outcomes.
The TEL-AML1 fusion gene results from a chromosomal translocation t(12;21)(p13;q22), which is one of the most frequently observed genetic abnormalities in childhood B-lineage ALL. Identifying this fusion gene not only confirms the diagnosis but also provides valuable prognostic information, helping clinicians tailor treatment strategies to individual patients. By enabling faster, evidence-based clinical decisions, the AML1 Fusion RT-PCR Kit supports improved disease management and better long-term results for patients.
Uses custom primers and fluorescent probes (FAM for TEL-AML1 and HEX for the internal control) to ensure precise detection, with reliable results demonstrated by detection of TEL-AML1 fusion gene with Ct ≤ 35.
RNase P internal control validates sample quality and workflow accuracy, minimizing false negatives and guaranteeing dependable outcomes.
Enables simultaneous detection of multiple targets in a single reaction, enhancing workflow efficiency, conserving reagents, and supporting rapid turnaround.
Optimized for major real-time PCR systems including QuantStudio™ 5, Bio-Rad CFX96, Roche LightCycler® 480, and RapiCycler 96, ensuring seamless integration into diverse laboratory setups.
Designed to deliver timely, consistent, and clinically actionable data to support critical decision-making in leukemia diagnostics.
Features optimized reagents and a 12-month stability profile, ensuring consistent performance and reliable outcomes across varying clinical laboratory conditions.
| Commercial Name | Cat No. | Pack Size |
|---|---|---|
| AML1 Fusion Real-Time PCR Test Kit | G2M802921 | 50 T |
Since its inception in 2016, Genes2me has been constantly striving towards setting a benchmark in the diagnostics space by introducing premium quality (Made in India) diagnostic kits which are CE-IVD, ISO-13485:2016, and ISO 9001:2015 certified, assuring our clients of unparalleled quality and compliance with international standards.
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