OncoFOCUS Panel v3.0

Identify Significant Somatic Mutations in Solid Tumors

The OncoFOCUS Panel v3.0 covers 250+ actionable mutations in 5 key oncogenes observed in lung, colorectal, and metastatic tumors including EGFR, KRAS, NRAS, and BRAF.

Benefits

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Profiling over 200+ significant somatic mutations in 5 key oncogenes.

Able to detect and quantify mutation frequencies as low as 5%.

Can utilise a minimal 20ng input DNA.

What it screens?

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GENE	COVERAGE	MUTATION
BRAF	Substitutions and deletions in codon 469 of exon 11; codons 594, 597, 600,601 of exon 15	25
EGFR	Substitutions, insertions, and deletions across exons 18, 19, 20, and 21. Includes key mutations such as L858R, L861Q, and T790M	125
KIT	Substitution mutations in exons 11, 13, and 17	6
KRAS	Substitution mutations across codons 12, 13 of exon 2; codons 59, 61 of exon 3; codons 117, 146 of exon 4	43
NRAS	Substitution mutations across codons 12, 13 of exon 2; codons 59, 61 of exon 3; codons 117, 146 of exon 4	31