Key Things to know About Whole Exome Sequencing (WES)

Whole exome sequencing (WES) is a process where the geneticists identify the changes in your genes. This new method has brought with its more practical uses in the medical world.

Since direct to consumer genetic testing has become common, as you can buy products that use hair or saliva samples to identify genetic traits, you can learn about your ancestry, ethnic traits, predisposition to certain medical conditions etc. The whole exome sequencing test is a little bit different because it is used to identify abnormalities in your genes that leads to specific health problems such as syndromes/disorder.

In this article, you can find out how whole exome sequencing is and what role it may play in your overall health care.

How Genes Work

The whole exome sequencing test in India is used to look for patterns that identify the genetic causes of a medical disease. It is good to know some basics of genetics if you have been thinking about utilizing WES.

A human being contains 23 pairs of chromosomes that contain a genetic code. These chromosomes are made up of long strands of nucleotide molecules. In order to produce key proteins, the body read these gene sequences.

Genes and Genomes

Genes are discrete segments of DNA, also known as Deoxyribonucleic Acid that carries all the genetic information of the body. Genes code for proteins in the body. That contains our body’s traits. Complete set of genetic information in one’s body is known as genome.

Exons

Exons are the functional part of genes that codes for proteins. A single gene contains several exons that code for more than one protein. Exons account for 1 to 2 per cent of the body’s total DNA. The whole exome sequencing genetic test at the entire exons in the whole genome is collectively known as exome.

Exome

So, if you are wondering, what is exome? It is the entire set of exons in of your genome. The whole exome sequencing blood test looks at the whole exome to detect any changes that are responsible for any medical condition.

What You Should Know About Whole Exome Sequencing

The whole exome sequencing genetic test in India uses your blood sample to analyse all the exons of your genome… The whole exome test uses a sequencing technique also known as Next generation sequencing to compare the nucleotide sequence of the sampled DNA with a standard or “normal” DNA sequence.

Whole exome sequencing can pick up the variations or mutations which are already known to cause disease. The test can also detect changes in the genetic code that have previously not been reported or associated with any specific disease/condition.

Where to Get Tested

There are many molecular diagnostics labs in India that run WES. You can take the test with Genes2ME, which has India’s leading diagnostics lab, providing the most accurate test results. The accredited test lab in India has advanced equipment’s, the latest technology, and trained personnel who can help you in your path of medical healing. The whole exome sequencing test price in India is reasonable compared to the medical benefits it offers you and your loved ones.

Genetic Counseling

As it happens with other genetic tests, the Whole exome test may be hard to decipher or understand. The field of genetics has grown so quickly that it is challenging to keep track of the advancement. But professionals trained in genetic counseling can help you throughout your journey to sort through such personal information.

A genetic counsellor can tell you why you should take the test, help you understand the process and benefits, reveal the whole exome sequencing cost in India, and help you navigate through the test results. These genetic counsellors will discuss the test results with you and how you can move forward using the information on your hand.