{"id":517,"date":"2022-02-19T07:20:21","date_gmt":"2022-02-19T07:20:21","guid":{"rendered":"https:\/\/genes2me.com\/blog\/?p=517"},"modified":"2022-02-19T07:20:21","modified_gmt":"2022-02-19T07:20:21","slug":"why-is-chromosomal-microarray-analysis-a-powerful-genetic-screening-test","status":"publish","type":"post","link":"https:\/\/genes2me.com\/blog\/2022\/02\/19\/why-is-chromosomal-microarray-analysis-a-powerful-genetic-screening-test\/","title":{"rendered":"Why is Chromosomal Microarray Analysis a Powerful Genetic Screening Test?"},"content":{"rendered":"\n
\"\"
Chromosomal Microarray Analysis<\/figcaption><\/figure>\n\n\n\n

The chromosomal microarray analysis test<\/a><\/strong> is one of the most popular tests recommended for children with developmental delays, congenital disabilities, autism spectrum disorder etc. Comprehensive genetic testing helps detect the presence of chromosomal abnormalities, like detecting an extra portion or a missing portion of a chromosome. It is an affordable analysis and screening technique to detect copy number variations in a chromosomal makeup and identify the reason for an underlying genetic condition or disease.<\/p>\n\n\n\n

Powerful Genetic Test\u00a0to Detect Chromosomal Abnormality<\/strong><\/h3>\n\n\n\n

Chromosomal Microarray Analysis in India\u00a0<\/strong>is available across the majority of the state-of-the-art and advanced molecular diagnostic labs<\/a><\/strong>. The powerful microarray test is a non-invasive method that analyses an individual’s genome and identifies chromosomal abnormalities like translocations, deletions, duplications, and extra chromosomes. It helps in detecting the copy number variants, the test help in the detection of autism spectrum disorder, developmental delays, seizures etc. It is a chip-based testing platform that simultaneously allows high-volume, automated DNA pieces analysis. The technique uses labels or probes that bind to specific chromosome regions, and a comparative analysis is made with the reference sample.<\/p>\n\n\n\n

Chromosomal Microarray Analysis and what it helps in detection<\/strong><\/h3>\n\n\n\n
\"\"
Chromosomal Microarray Analysis <\/figcaption><\/figure>\n\n\n\n

The Chromosomal microarray Analysis is used as one of the most accurate\u00a0first-trimester screening for Trisomies 21 and 18<\/a><\/strong>. It is a recommended prenatal genetic testing that helps detect chromosomal abnormality or copy number variant as early as the first trimester. As a frontline high-resolution diagnostic procedure, it helps identify sub-microscopic microdeletions, microduplications, trisomy, recurring pregnancy loss, and ultrasound abnormalities. CMA is a technique that helps detect even unbalanced rearrangements of chromosomes like translocations.<\/p>\n\n\n\n

The CMA test help in accurately detecting the presence of Trisomy 21 (Down Syndrome) and Trisomy 18 (Edward’s Syndrome). The prenatal CMA compares specific regions of an unborn baby’s DNA to a normal genome. Detection of the microduplication and microdeletion in the chromosome can lead to genetic disorders and intellectual or physical abnormalities in the newborn child. A popular\u00a0Down Syndrome screening test<\/a>\u00a0<\/strong>provides accurate information on Trisomy 21 during the first trimester.<\/p>\n\n\n\n

Who is Chromosomal Microarray Analysis Recommended for?\u00a0<\/strong><\/h3>\n\n\n\n